circulating fetal cells

How are Circulating Fetal Cells Detected?

Detecting circulating fetal cells involves several steps:
1. Blood Sample Collection: A maternal blood sample is collected.
2. Cell Enrichment: Techniques such as density gradient centrifugation or magnetic cell sorting are used to enrich the fetal cells from the maternal blood.
3. Identification and Analysis: Fluorescence in situ hybridization (FISH), quantitative polymerase chain reaction (qPCR), and next-generation sequencing (NGS) are commonly used to identify and analyze the genetic material of the fetal cells.

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