What are the Challenges in Histological Cancer Detection?
Despite advancements, histological cancer detection faces several challenges:
Sampling Error: A biopsy might not capture the most representative tissue sample, potentially missing the cancerous cells. Interobserver Variability: Differences in interpretation among pathologists can lead to inconsistent diagnoses. Tumor Heterogeneity: Variability within the tumor itself can make it difficult to identify all cancerous areas. Technical Artifacts: Issues during tissue processing, sectioning, or staining can introduce artifacts that obscure accurate diagnosis.
