Ki-67 labeling has numerous applications in both clinical and research settings:
- Cancer Diagnosis and Prognosis: Ki-67 is used to assess the proliferative index of tumors, aiding in the grading of cancers such as breast cancer, prostate cancer, and lymphomas. - Treatment Monitoring: Tracking changes in Ki-67 levels can help evaluate the effectiveness of therapies aimed at reducing cell proliferation. - Tissue Regeneration Studies: Ki-67 can be used to study the regenerative capacity of tissues in various experimental models. - Stem Cell Research: It helps in identifying proliferating stem cells in various niches.