What are the Applications of DNase I in Histology?
RNA extraction: DNase I is used to remove contaminating DNA during RNA extraction from tissue samples. Cell culture: DNase I prevents the clumping of cells by degrading extracellular DNA in cell culture systems. Apoptosis detection: DNase I aids in the identification of apoptotic cells by cleaving DNA into characteristic fragments. Histological staining: DNase I treatment can enhance the specificity of histological stains by removing DNA that may bind non-specifically.
