Why is DNase I Important for Histological Techniques?
DNase I is crucial for histological techniques involving in situ hybridization and immunohistochemistry. During in situ hybridization, DNase I treatment helps to reduce background signals caused by non-specific binding of probes to DNA. In immunohistochemistry, DNase I is used to avoid cross-reactivity and ensure the specificity of antibody binding to antigen targets.
