3D reconstruction has numerous applications across various fields of biomedical research:
Neuroscience: It enables the detailed mapping of neural circuits and the study of brain connectivity. Techniques like serial section electron microscopy have been crucial in this field. Developmental Biology: Researchers can study the dynamic changes in tissue architecture during embryonic development. Pathology: 3D models help in understanding disease progression, such as tumor growth and metastasis, by visualizing the spatial relationships between different cell types and tissues. Regenerative Medicine: It aids in assessing tissue regeneration and the integration of engineered tissues with the host body. Cardiology: Visualization of the complex structure of the heart and blood vessels can improve our understanding of cardiovascular diseases.
