What Are Some Pathological Implications of Cytoskeletal Dysfunction?
Dysfunction in cytoskeletal components can lead to a variety of diseases. For instance, mutations in intermediate filament proteins can cause epidermolysis bullosa simplex, a skin disorder. Defects in microtubules are associated with neurodegenerative diseases like Alzheimer's. Understanding cytoskeletal arrangements in histology can provide insights into the diagnosis and treatment of these conditions.
