What Are Some Histological Techniques Used to Study Bacterial Infections?

Several histological techniques are employed to study bacterial infections. These include traditional staining methods like Gram staining to differentiate between Gram-positive and Gram-negative bacteria, and special stains like Ziehl-Neelsen for acid-fast bacteria. Immunohistochemistry can be used to identify specific bacterial antigens within tissues. Fluorescence in situ hybridization (FISH) allows for the detection of bacterial DNA within tissue sections, providing a high level of specificity.