LSIL and HSIL are both types of squamous intraepithelial lesions, but they differ in their severity and risk of progression. While LSIL represents mild dysplasia confined to the lower third of the epithelium, HSIL involves more severe abnormalities that extend into the upper two-thirds of the epithelium. HSIL has a higher risk of progressing to invasive cervical cancer if left untreated.
