gene fusions

What Are Some Common Gene Fusions in Cancer?

Several gene fusions are commonly associated with different types of cancer:
- BCR-ABL: Found in chronic myeloid leukemia (CML) and some acute lymphoblastic leukemias (ALL).
- ETV6-RUNX1: Common in childhood acute lymphoblastic leukemia (ALL).
- EWS-FLI1: Characteristic of Ewing's sarcoma.
- TMPRSS2-ERG: Found in a significant percentage of prostate cancers.

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