Research on gene fusions is rapidly evolving with advancements in technology:
- Next-Generation Sequencing (NGS): This high-throughput technology allows for the comprehensive analysis of gene fusions across the entire genome. - Single-Cell Sequencing: Provides insights into gene fusions at the single-cell level, offering a more detailed understanding of tumor heterogeneity. - CRISPR-Cas9: Gene-editing technology is being used to model gene fusions in the lab, providing valuable insights into their role in disease.
