- Studying Cell Signaling: Co-IP can be used to identify interactions between signaling molecules in different tissue types. - Cancer Research: By identifying protein interactions in tumor tissues, Co-IP can help elucidate mechanisms of tumorigenesis and identify potential targets for therapy. - Neuroscience: Understanding protein interactions in brain tissues can provide insights into neural function and neurodegenerative diseases. - Developmental Biology: Co-IP can help in studying the interactions between proteins involved in tissue development and differentiation.