Proerythroblasts are the earliest precursor cells in the erythropoietic lineage, which eventually give rise to mature red blood cells (RBCs). These cells originate from hematopoietic stem cells and undergo a series of developmental stages, culminating in the formation of erythrocytes. Proerythroblasts are characterized by their large size, round nuclei, and basophilic cytoplasm, indicative of high ribosomal RNA content essential for hemoglobin synthesis.
