Several key features distinguish proerythroblasts: - Size and Shape: They are large cells with a diameter of approximately 12-20 µm. - Nucleus: The nucleus is large, round, and occupies most of the cell volume. It has a fine chromatin pattern with one or more nucleoli visible. - Cytoplasm: The cytoplasm is intensely basophilic due to the high content of ribosomal RNA, essential for protein synthesis. - Mitotic Activity: Proerythroblasts are mitotically active, undergoing division to produce more differentiated erythroid precursors.
