MASPs are enzymes that become activated upon binding of MBL or ficolins to pathogen surfaces. There are three main types of MASPs: MASP-1, MASP-2, and MASP-3. Each performs distinct but overlapping functions in the activation of the complement system. MASP-1 and MASP-2 are primarily responsible for cleaving complement components, whereas MASP-3's role is less understood but believed to be regulatory.