What are the Consequences of Aneuploidy in Tissues?
Aneuploidy can have significant implications on tissue structure and function. In developing tissues, it can lead to congenital abnormalities and developmental disorders. In adult tissues, aneuploidy is commonly associated with neoplastic transformation, contributing to the progression of various cancers. For instance, aneuploidy is a hallmark of colorectal cancer and is often observed in breast cancer tissues.