What are Common Staining Techniques in Dermatology?
Several staining techniques are employed in dermatological histology to highlight different tissue components: - Hematoxylin and Eosin (H&E): The most common staining method, H&E provides a general overview of tissue architecture. - Periodic Acid-Schiff (PAS): Highlights polysaccharides and mucosubstances, useful in diagnosing fungal infections and mucinous lesions. - Masson's Trichrome: Differentiates between collagen, muscle, and fibrin, aiding in the assessment of fibrosis and connective tissue disorders. - Immunofluorescence: Detects specific proteins and antigens using fluorescent-labeled antibodies, often used in autoimmune blistering diseases.
