What are the Applications of Electron Microscopy in Dermatology?
Electron microscopy provides ultra-high resolution images, allowing for the observation of cellular and subcellular structures. In dermatology, it is used to study: - Basement Membrane Zone: Assessing its integrity in blistering disorders. - Melanosomes: Understanding their distribution and abnormalities in pigmentary disorders. - Desmosomes and Hemidesmosomes: Examining their role in cell adhesion and integrity in diseases like pemphigus and epidermolysis bullosa.
