What are common histological changes seen in liver diseases?
Liver diseases can cause various histological alterations in liver tissue:
Steatosis – Also known as fatty liver, it is characterized by the accumulation of fat droplets within hepatocytes. Fibrosis – The excessive deposition of extracellular matrix proteins, leading to scarring and architectural distortion of the liver. Cirrhosis – A late stage of liver scarring characterized by the formation of nodules and disruption of normal liver architecture. Hepatitis – Inflammation of liver tissue, which can be caused by viral infections, alcohol, or autoimmune diseases. It is often accompanied by necrosis and apoptosis of hepatocytes. Cholestasis – Impaired bile flow resulting in the accumulation of bile within the liver, leading to hepatocyte injury and jaundice.
