In histology, the study of ZIC3 involves several techniques to visualize and understand its expression patterns and functional roles. Immunohistochemistry (IHC) is commonly used to detect ZIC3 protein in tissue sections. This technique involves the use of antibodies specific to ZIC3, which bind to the protein and are then visualized using various detection methods. In situ hybridization (ISH) is another technique used to detect ZIC3 mRNA in tissues, providing insights into the gene's expression patterns during development.
