How Is Mitochondrial Apoptosis Studied in Histology?
In histology, mitochondrial apoptosis can be studied using a variety of techniques. Immunohistochemistry can be employed to detect the expression of pro-apoptotic and anti-apoptotic proteins. TUNEL (Terminal deoxynucleotidyl transferase dUTP nick end labeling) assay can be used to identify DNA fragmentation, a hallmark of apoptosis. Additionally, electron microscopy can reveal ultrastructural changes in mitochondria associated with apoptosis.
