Can Mitochondrial Apoptosis Be Therapeutically Targeted?
Given its central role in cell death, mitochondrial apoptosis is a promising target for therapeutic intervention. In cancer therapy, drugs that mimic the action of pro-apoptotic proteins or inhibit anti-apoptotic proteins are being developed. Conversely, in conditions characterized by excessive apoptosis, strategies to enhance the activity of anti-apoptotic proteins or inhibit pro-apoptotic pathways are being explored.