How is Metabolic Dysfunction Diagnosed Using Histology?
Diagnosis of metabolic dysfunction through histology involves several steps:
1. Tissue Biopsy: Obtaining a tissue sample from the affected organ. 2. Histological Staining: Using specific stains like Hematoxylin and Eosin (H&E), Periodic acid–Schiff (PAS), or Oil Red O to highlight abnormalities. 3. Microscopic Examination: Observing the stained tissues under a microscope to identify structural changes. 4. Molecular Techniques: Employing techniques like immunohistochemistry to detect specific proteins or enzymes.