Researchers use various techniques to study initiator tRNA in histology. Immunohistochemistry can be used to detect the presence and distribution of initiation factors and ribosomal components within tissues. Additionally, in situ hybridization techniques can help localize mRNA and tRNA within cells, providing insights into the cellular mechanisms of protein synthesis. Electron microscopy can also be used to visualize ribosomal structures and interactions between initiator tRNA and the ribosome at the ultrastructural level.