The process of image annotation involves several steps:
1. Image Acquisition: High-resolution images of tissue samples are captured using digital pathology scanners or microscopes.
2. Preprocessing: Images are often preprocessed to enhance contrast, remove noise, or adjust color balance for better visualization.
3. Annotation: Using dedicated software, regions of interest are marked and labeled. This can include drawing boundaries around tissues, marking individual cells, or highlighting specific histological features.
4. Validation: Annotated images are reviewed and validated by experts to ensure accuracy and consistency.