What are the Histological Features of Malignant Neoplasms?
Malignant neoplasms exhibit several histological features that distinguish them from benign growths: - Poorly defined margins: The borders are often irregular and infiltrative. - Cellular atypia: Cells show significant deviations from normal morphology, including variations in size and shape (pleomorphism), nuclear abnormalities, and increased nuclear-to-cytoplasmic ratio. - High mitotic activity: There is an increased number of mitotic figures, some of which may be abnormal. - Invasion of surrounding tissues: Malignant cells penetrate adjacent tissues and can spread to other parts of the body (metastasis).
