IL-17 has a significant role in the innate and adaptive immune systems. It stimulates the production of other cytokines such as TNF-α and IL-6, and chemokines like IL-8, which in turn recruit neutrophils to the site of infection or inflammation. This recruitment is essential for the containment and eradication of pathogens. Additionally, IL-17 can enhance the production of antimicrobial peptides by epithelial cells, making it an important player in mucosal immunity.
