How is Histology Used in Diagnosing Cardiomyopathies?
Histology plays a crucial role in the diagnosis of cardiomyopathies:
Endomyocardial Biopsy: This procedure is often performed to obtain tissue samples. The histological analysis can reveal specific patterns of cellular and extracellular abnormalities that help in diagnosing the type of cardiomyopathy. Immunohistochemistry: This technique can identify specific proteins and cellular components, such as amyloid deposits or viral inclusions, aiding in the diagnosis of conditions like RCM or myocarditis-related DCM. Genetic Testing Correlation: Histological findings can be correlated with genetic testing results to confirm hereditary forms of cardiomyopathy, such as HCM or ARVC.
