In histology, gastric acid and its effects on the stomach lining are studied using various staining techniques. The hematoxylin and eosin (H&E) stain is commonly used to visualize the general structure of the stomach tissue, including parietal cells. Specialized stains like the Periodic acid-Schiff (PAS) stain can highlight the mucous layer, while immunohistochemical techniques can identify specific cell types and proteins involved in acid secretion.