Disruption of blood vessels can result from various factors, including trauma, inflammation, atherosclerosis, and hypertension. Trauma can cause direct physical damage to blood vessels, leading to hemorrhage and potential tissue ischemia. Inflammation, often a response to infection or injury, can weaken the vessel walls and lead to aneurysm formation or rupture. Atherosclerosis involves the accumulation of lipid plaques within the arterial walls, narrowing the lumen and increasing the risk of vessel rupture. Hypertension, or high blood pressure, exerts excessive force on the vessel walls, contributing to their weakening and potential rupture.