In histological studies, the expression of CXCR5 can be detected using immunohistochemistry (IHC) or immunofluorescence techniques. These methods involve the use of specific antibodies that bind to CXCR5, allowing for its visualization under a microscope. In IHC, the binding of the antibody is typically visualized using an enzyme-linked detection system that produces a colorimetric reaction, whereas in immunofluorescence, fluorescent dyes are used to label the antibody, making it possible to observe the protein's distribution within tissues.
