What Are the Challenges in Understanding Cellular Context?
One of the main challenges in understanding cellular context is the complexity and dynamic nature of the tissue microenvironment. Cells are constantly interacting with their surroundings, and these interactions can change over time. Additionally, the heterogeneity of tissues, with different cell types and ECM components, adds another layer of complexity. Advances in single-cell analysis and spatial transcriptomics are helping to address these challenges by providing more detailed and comprehensive views of cellular context.
