In histology, bone resorption can be studied using various techniques: - Histochemical Staining: Techniques such as TRAP (Tartrate-Resistant Acid Phosphatase) staining identify osteoclasts. - Microscopy: Electron microscopy provides detailed images of osteoclasts and their attachment to bone surfaces. - Immunohistochemistry: This technique detects specific proteins involved in resorption, such as RANKL and cathepsin K.
