1. User-Friendly Interface: The tool should be intuitive and easy to use for both beginners and experts. 2. Multiple Annotation Types: Support for various annotation forms such as points, lines, polygons, and freehand drawing. 3. Scalability: Ability to handle large datasets and high-resolution images without compromising performance. 4. Collaboration: Features that allow multiple users to annotate and review images simultaneously. 5. Integration: Compatibility with other histological analysis software and databases. 6. Data Export: Options to export annotated images and data in various formats for further analysis or publication.