How Does Rational Design Address Challenges in Histology?
Rational design helps to overcome various challenges in histology, such as tissue autofluorescence, which can obscure specific signals in fluorescence microscopy. By designing more specific fluorophores or employing techniques like spectral unmixing, researchers can minimize these issues. Additionally, rational design can optimize tissue processing protocols to preserve delicate structures and prevent artifacts that might arise during sectioning or staining.
