Despite its potential, proteomics faces several challenges:
- Complexity of the Proteome: The dynamic and complex nature of the proteome, with its vast array of post-translational modifications, poses significant analytical challenges. - Sensitivity and Specificity: Detecting low-abundance proteins in the presence of high-abundance proteins requires highly sensitive and specific techniques. - Data Analysis: The large amount of data generated from proteomic studies necessitates advanced bioinformatics tools and expertise for proper interpretation.