How Does Nutrient Deprivation Affect Tissue Function?
Different tissues respond variably to nutrient deprivation. For instance:
- Liver: The liver is a central organ in nutrient metabolism and shows increased gluconeogenesis and ketogenesis during nutrient deprivation. Histologically, you may observe increased glycogen depletion and lipid accumulation. - Muscle: Muscle tissues undergo protein catabolism, leading to muscle wasting. Histological analysis may reveal atrophy of muscle fibers. - Brain: The brain is highly sensitive to glucose deprivation. Histological studies can show neuronal damage and increased apoptotic cells.