What Are the Histological Markers of Nutrient Deprivation?
One of the hallmarks of nutrient deprivation is the increased presence of autophagic structures, observable under electron microscopy. Additionally, histological staining techniques can identify the accumulation of lipid droplets, indicative of altered lipid metabolism. Immunohistochemistry can be used to detect markers such as LC3 and p62, which are involved in the autophagy process.