How Does Lead Poisoning Affect Histological Structures?
Lead poisoning can cause significant alterations in histological structures. In the liver, it may lead to hepatocyte necrosis, periportal fibrosis, and chronic inflammation. In the kidneys, it can cause tubular atrophy, interstitial fibrosis, and glomerulosclerosis. In the brain, lead deposition can result in neuronal degeneration, gliosis, and microglial activation. These changes can be visualized using histological staining and microscopy.