The liver plays a central role in lipid metabolism, and hyperlipidemia can lead to various histological alterations in hepatic tissue:
Hepatic Steatosis: Excessive accumulation of triglycerides within hepatocytes, known as fatty liver, can occur. Histologically, this is characterized by large lipid droplets displacing the nucleus to the cell periphery. Liver Inflammation: Chronic lipid accumulation can lead to non-alcoholic steatohepatitis (NASH), characterized by hepatocyte ballooning, inflammation, and fibrosis.
