How Does Homophilic Binding Impact Tissue Organization?
Homophilic binding is fundamental for tissue organization and morphogenesis. During embryonic development, cells need to adhere selectively to form organized structures like epithelial layers and neural tissues. Homophilic interactions ensure that cells of the same type preferentially stick together, leading to the formation of distinct tissue layers and compartments. This selective adhesion is critical for processes such as organogenesis and wound healing.