How Does Histology Help in Diagnosing Metabolic Disorders?
Histological examination of tissue samples can reveal structural abnormalities that are characteristic of specific metabolic disorders. For instance, in diabetes mellitus, histological analysis of pancreatic tissue may show a reduction in the number of insulin-producing beta cells. In lysosomal storage diseases, histology can reveal the accumulation of undigested substrates within lysosomes, leading to cellular damage.