How Does Corneal Edema Affect Histological Features?
Corneal edema primarily affects the stroma and endothelium. Histological examination reveals several key changes:
Stromal Swelling: The stroma becomes thickened due to fluid accumulation between collagen fibrils. Endothelial Cell Damage: Loss or dysfunction of endothelial cells leads to reduced fluid regulation. Disruption of Collagen Architecture: The orderly arrangement of collagen fibrils in the stroma is disrupted, leading to increased light scattering and loss of transparency.
