How Do Tumor Microenvironments Influence Evolution?
The tumor microenvironment plays a significant role in tumor evolution. It consists of various cell types, extracellular matrix components, and signaling molecules that interact with tumor cells. Histological analysis can reveal how factors such as hypoxia, immune cell infiltration, and angiogenesis influence tumor growth and progression. These interactions can create selective pressures that drive the evolution of more aggressive tumor phenotypes.
