How Do Progesterone Receptors Affect Breast Tissue?
In breast tissue, PRs are involved in the regulation of mammary gland development and function. Progesterone, through its receptors, promotes the growth and differentiation of mammary epithelial cells, which is crucial for lactation. Abnormal PR signaling in breast tissue has been linked to breast cancer, making PR status an important marker in the diagnosis and treatment of the disease.
