What are the Different Isoforms of Progesterone Receptors?
There are two main isoforms of progesterone receptors, known as PR-A and PR-B. These isoforms arise from a single gene but have distinct functions. PR-B is generally considered the full-length receptor and is the primary mediator of progesterone's effects. PR-A, on the other hand, acts as a repressor of PR-B and other steroid receptors, thereby fine-tuning the hormonal response.
