How do pathologists distinguish between squamous epithelial cells and urothelial cells?
Squamous epithelial cells and urothelial cells can be found in the urinary tract but have different morphological features. Squamous epithelial cells are flat with a central nucleus, whereas urothelial cells can appear more rounded or polygonal. Immunohistochemistry can be used to identify specific markers like CK20 for urothelial cells.