What is the importance of distinguishing between hepatocytes and cholangiocytes?
Hepatocytes and cholangiocytes are both found in the liver but serve different functions. Hepatocytes are involved in metabolic processes while cholangiocytes line the bile ducts. Distinguishing between these cells is essential in diagnosing liver diseases, such as hepatitis and cholangiocarcinoma. Immunohistochemical staining for markers like CK7 and CK19 can aid in differentiating between these cell types.
