The accumulation of lipid plaques within the arterial walls leads to the narrowing of the lumen, which restricts blood flow. This can result in a condition known as ischemia, where tissues receive insufficient blood supply. If a plaque ruptures, it can lead to the formation of a thrombus (blood clot) that further obstructs the artery. The reduced blood flow and potential for clot formation significantly increase the risk of acute cardiovascular events.
