IDCs are essential for the activation of naive T-cells. They capture, process, and present antigens on their surface via major histocompatibility complex (MHC) molecules. This interaction between MHC-peptide complexes on IDCs and T-cell receptors on T-lymphocytes is crucial for the initiation of adaptive immune responses. Additionally, IDCs secrete cytokines that modulate the immune response, further enhancing their role as key mediators of immunity.
